Rebalancing glucolipid metabolism and gut microbiome dysbiosis by nitrate-dependent alleviation of high-fat diet-induced obesity

Introduction High-fat diet (HFD)-induced obesity is accompanied by compromised nitric oxide (NO) signaling and gut microbiome dysregulation.Inorganic dietary nitrate, which acts as a NO donor, exerts beneficial effects on metabolic disorders.Here, we evaluated the effects of dietary nitrate on HFD-induced obesity and provided insights into the unde

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Extreme events, loss, and grief - an evaluation of the evolving management of climate change threats on the Great Barrier Reef

Coral reefs across the world have demonstrated an incredible resilience to disturbance, having persisted for over 200 million years withstanding local, short-term shocks such as cyclones and bleaching events, as well as large-scale, long-term global changes such as sea-level fluctuations.However, there are now many persistent and growing threats to

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